Explore tools developed by and/or used in VHP4Safety.
You can search for a tool that you know using the search box below. Alternatively, you can filter the tools with respect to the case studies' flow step that they belong to and/or the regulatory question that they are associated with. Use the "Filters" button to show filter options, then "Apply Filter" to see results, and click "Clear Filter" to reset the filters.
The Virtual Human Platform implements the generic risk assessment workflow as a process flow comprising of five steps.
A tool that supports Adverse Outcome Pathway (AOP) development by extracting key scientific entities and their relationships from literature.
A web-based tool for building, visualizing and analyzing Adverse Outcome Pathway (AOP) networks.
A REST API for creating and accessing content in the AOP-Wiki database.
A graphical interface for creating, preloading and exporting SPARQL queries tailored to your usecases.
A user-interface for preprocessing and statistically analyzing RNA-sequencing and microarray transcriptomics data.
A repository dedicated to the inventory and acquisition of high-quality mathematical models pertaining to biological and biomedical systems.
A software tool for predicting metabolites from SMILES-formatted chemical inputs.
A software tool for high-dimensional dose-response modeling and analysis.
A framework for mapping identifiers across biological databases and related sources.
A webservice for generating chemical structure images from SMILES inputs.
An intuitive user interface for creating gene-regulatory and biochemical network diagrams.
An online database for searching chemical, toxicity and exposure information.
An open-source software for simulating, analyzing and visualizing biochemical networks using a wide range of methods.
An online model for predicting water-octanol distribution coefficient (logD) of chemical compounds with confidence estimates.
An online service for automatically extracting chemical structure depictiions from PDFs and images.
An online repository for inventarisation of official reports from the European Medicines Agency concerning chemical evaluation and safety monitoring.
A web-accessible registry for managing, sharing and organising research data and research assets.
An open source RDF-based data management platform for importing and exporting research-relevant metadata
A Dutch online resource for gathering data on the pharmacology, adverse effects, and prices of all pharmaceutical products available in the Netherlands.
An open source web application for building predictive models from biologically annotated chemical structures using predefined workflows.
An online search engine for (scientific) literature.
Online search engine for Google.
An in-house data inventory produced by the Joint Research Centre (JRC) for provision of independent scientific advice and support to policies of the European Union.
An online tool for answering questions about lipid metabolism and related toxicology/biology using MINERVA pathway knowledge, live web research and AI-generated summaries.
A Python-based notebook for identifying potential MCT8 inhibitors and related molecular events linked to developmental thyroid toxicity from maternal thyroid hormone deprivation.
An online service for analyzing transcriptomic data in the context of molecular Adverse Outcome Pathways (AOPs), supporting data upload or demo datasets for gene selection, visualization and Key Event (KE) enrichment analysis.
An online database from the NIH Office of Dietary Supplements that lets you explore information from more than 200,000 dietary supplement labels sold in the United States.
An online assistant for using the OECD QSAR Toolbox to analyze chemicals, assess hazards and generate AI-based summary reports.
Maps for illustrating biological processes behind toxicological risks using a standardized graphical notation.
An online physiologically based pharmacokinetic model for organophosphates
An online service for parsing chemical IUPAC names into a machine-readable chemical identifiers.
An interactive tool for visualizing and predicting key events (KEs) and adverse outcomes (AOs) over time using ODE-based qAOP models, illustrated with VHP4Safety case studies.
An online tool for chemical activity prediction for various endpoints using target-specific and pretrained QSAR models.
An R Shiny interface for the R-ODAF framework that provides standardised RNA-seq differential expression analysis for regulatory toxicology applications.
A webservice for prediction of protein-structure and reactivity based (P450) site-of-metabolism.
An online service for conduction of literature review, data extraction and systematic review.
A software for supporting chemical hazard assessment and enhancing mechanistic knowledge of substances in a cost-effective way.
An online tool for harmonizing in vitro toxicity test methods using Large Language Models, based on the ToxTemp template where it extracts details from protocols, publications or lab notes to create structured draft responses.
An online application for implementation of weighted gene co-expression network analysis (WGCNA) derived from publicly available transcriptomic datasets from the TG-GATEs database.
A collection of ontology with names, abrreviations and definitions of the terminology that is used within the VHP4Safety project.
A Wikibase instance for storing and presenting information about toxic, safe and potentially toxic compounds related to the VHP4Safety project.
A Synia-based graphical user interface to the content of the VHP4Safety Wikibase.
An Adverse Outcome Pathway (AOP) portal on WikiPathways for exploring the molecular basis of AOPs and their key events (KEs).
A web application for visualization of Adverse Outcome Pathway (AOP) networks and interactive exploration of AOPs for two liver outcomes.
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