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inTESTine™

TNO recently developed InTESTine™ in order to study the absorption and translocation of pharmaceutical, biological and nutritional compounds across the intestinal wall in a physiologically relevant model. This system uses fresh ex vivo intestinal tissue mounted into a two compartment model. So far, this has been the missing link in our toolbox to accurately predict absorption, oral bioavailability and PK of compounds.

Summary

TNO recently developed InTESTine™ in order to study the absorption and translocation of pharmaceutical, biological and nutritional compounds across the intestinal wall in a physiologically relevant model. This system uses fresh ex vivo intestinal tissue mounted into a two compartment model. So far, this has been the missing link in our toolbox to accurately predict absorption, oral bioavailability and PK of compounds.

Key details
Vendor
TNO
Catalog number
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SOP
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Type
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Citation
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Last updated
12 Nov 2026
Safety Assessment Workflow

Kinetics Q2

Regulatory question

Thyroid Mediated Developmental Neurotoxicity (b)

Provider
TNO
At this moment no documentation is (known to be) registered in Taxila.nl or ELIXIR TeSS.

Contact

  • No contact information available.

No publications available.