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The Virtual
Human Platform

Delivering precision safety testing through human data-driven tools and real-world use cases

Tools
Select our VHP tools to streamline your risk assessment process and get results relevant to your research.
Case Studies
Have a look at our case studies to see how multiple VHP tools can be combined to best answer your research question.
Data
Find all the (meta)data you need to use the VHP tools and run workflows as efficiently as possible.

About VHP4Safety

The Virtual Human Platform (VHP) was developed through the VHP4Safety project to support chemical and pharmaceutical safety testing. VHP aims to facilitate the prediction of harmful effects of chemicals and pharmaceuticals by integrating human physiology, chemical properties, and biological pathway disturbances. VHP provides you with human-relevant tools and models for precision safety evaluation, helping you reduce reliance on laboratory animals. With VHP, you can assess chemicals for human use, including vulnerable populations such as infants, the elderly, and individuals with health conditions.

As a user, the platform offers you

  • Documentation: Access clear, user-friendly guides at VHP4Safety Docs. You can find cloud service descriptions, tutorials and example workflows that help you combine multiple services for more complex analyses.
  • Glossary: Quickly understand key terms using the VHP4Safety Glossary. It is designed to make collaboration easier and to ensure that your are always on the same page as other users and project members.
  • Cloud services: Take advantage of the VHP Cloud, which hosts a wide range of services for your case studies. You can explore the catalog, request additional services or contribute to new ones which are tailored to help you achieve your research goals.
  • Sciencrew Network: Stay informed with updates on project members, key developments, and social insights through the website. This keeps you connected to the wider VHP4Safety community and its expertise.

By using these resources, you can perform more accurate, ethical, and user-friendly chemical and pharmaceutical safety assessments, moving beyond traditional animal testing and leveraging human-centered data.

Traditional animal studies often fail to predict toxicity in humans. VHP4Safety addresses this challenge by focusing on human-relevant data and providing the tools, services, and workflows needed to translate this data into actionable insights. The platform considers human-relevant scenarios such as age, gender, disease states, and exposure timing, and evaluates chemicals from pharmaceuticals, consumer products, and the chemical industry, all while meeting the needs of regulators and stakeholders. The development of VHP has followed three research lines: building the platform infrastructure and services, generating and integrating high-quality human-relevant data, and ensuring stakeholder acceptance and sustainability. By combining these approaches, VHP accelerates the global shift toward human-centered safety assessment.

VHP was developed through the VHP4Safety project, funded by the Dutch Research Council (NWO) programme entitled the ‘Dutch Research Agenda: Research on Routes by Consortia (NWA-ORC)’. The project ran from June 1, 2021, for five years, paving the way for a future of safety assessments based entirely on human data.

Project Partners

Collaboration and support in innovation.

Connect with us for a chat or support

Got questions or just want to connect? Use the form below, or contact us on LinkedIn, GitHub, or via email and we’ll get back to you as soon as possible.