The Virtual
Human Platform

Towards safety assessment based on human data

Tools

Select any of the VHP tools to streamline your risk assessment process and get results relevant to your research.

41 tools available

Case Studies

Have a look at our case studies to see how multiple VHP tools can be combined to best answer your research question.

3 case studies

Data

Find all the (meta)data you need to use the VHP tools and run workflows as efficiently as possible.

0 datasets

About VHP4Safety

The Virtual Human Platform (VHP) was developed through the VHP4Safety project to support chemical and pharmaceutical safety testing. By developing in silico tools and in vitro models, we provided a platform for precision safety testing that aims to eliminate the need for laboratory animals. VHP helps risk assessors evaluate the safety of chemicals for human use, focusing on vulnerable groups like infants, the elderly, and individuals with health conditions.

Our Mission

VHP aims to facilitate the prediction of harmful effects of chemicals and pharmaceuticals by integrating human physiology, chemical properties, and biological pathway disturbances. The platform supports:

Human-relevant scenarios, such as age, gender, disease states, and exposure timing;
Chemicals from pharmaceuticals, consumer products, and the chemical industry;
The needs of regulators and stakeholders.

VHP represents a major step forward in moving away from animal testing by providing tools based on human data.

Traditional animal studies often fail to predict toxicity in humans. VHP aims to overcome this by focusing on human-relevant data and providing the needed services and workflows to translate this data into new insights. The platform has been developed within three research lines:

Building the platform
Generating and integrating human-relevant data
Ensuring stakeholder acceptance and sustainability

With global efforts to reduce animal testing, VHP accelerates the shift to human-centered safety assessment.

VHP was developed through the VHP4Safety project, funded by the Dutch Research Council (NWO). The project ran from June 1, 2021, for five years, paving the way for a future of safety assessments based entirely on human data.